FAQ


Quand et à quelle fréquence dois-je faire tester mes animaux pour une pathologie cardiaque héréditaire ?

Il n'existe pas de réponse précise à cette question et, à l'heure actuelle, aucun consensus n'a été établi pour toutes les pathologies. Les directives peuvent varier d'un pays à l'autre et il est recommandé de consulter le club de la race concernée.  ACAPULCO suit les directives établies par la Société Européenne de Cardiologie Vétérinaire (ESVC), par le schéma établi par la Société Vétérinaire Cardiovasculaire Britannique (www.bsava.org.uk/vcs/) et les recommandations du Professor Kittleson pour les Maine Coons.

DIRECTIVES D'ACAPULCO

Cardiomyopathie dilatée (CMD) chez le chien: si les animaux sont utilisés à des fins de reproduction, un dépistage annuel est recommandé avant la première saillie jusqu'à la mort de l'animal. En effet, la maladie se développe souvent plus tardivement dans la vie de l'animal.

Cardiomyopathie hypertrophique (CMH) chez le chat : si les animaux sont utilisés à des fins de reproduction, un dépistage annuel est recommandé avant la première saillie. Dans la race Maine Coon, la plupart des mâles auront développé la maladie avant l'âge de 2 ans (signes échocardiographiques) et les femelles avant l'âge de 3 ans. Cependant, il existe des exceptions et un développement plus tardif de la pathologie n'est pas exclu. La plupart des autres races développeront également la maladie à un jeune âge.

Sténose aortique (AS) chez le chien: le dépistage peut être fait par auscultation uniquement mais, chez les chiens présentant un souffle de grade 1 ou 2, une échocardiographie Doppler est fortement recommandée afin de déterminer avec précision le gradient de pression créé par la sténose. Le dépistage peut débuter à un très jeune âge mais la certification ne sera valable qu'une fois que le chien sera âgé d'au moins 1 an au moment du dépistage car la gravité de la pathologie peut changer durant la croissance. Un dépistage répétitif n'est pas nécessaire car la sténose aortique a tendance à rester stable après la croissance chez la plupart des chiens (mais pas tous).

SPECIFIC BRITISH RECOMMENDATIONS FOR BOXER BREEDERS REGARDING SAS (Dr Bruce Catanagh)

A. In the case of adults, ie, over 12 months of age:

1. All stock should be screened by designated cardiologists
- those which are free of heart murmurs (Grade 0) may be considered free of aortic (and pulmonic) stenosis, and suitable for breeding purposes.
- those which have only minor (Grade 1) murmurs may, for the moment, be accepted as normal and therefore suitable for breeding purposes.
2. Stock with Grade 2 murmurs may be rescreened (up to three times).
- those which on any rescreening obtain a Grade 1 score, or are even found to be murmur-free, may be considered suitable for breeding;
- those which are consistently found to have Grade 2 or louder murmurs should normally be discarded for breeding purposes, unless, in the case of bitches, there is no alternative other than to disband the whole of a kennel's breeding stock, when,

1. Selected bitches should be mated only to stud dogs that are considered to be normal (as described above), preferably murmur-free.

2. At most only one or two litters should be taken with the objective of breeding a murmur-free replacement.
In the case of dogs with murmurs consistently no louder than Grade 2, Doppler echocardiography  may be a further option. Those with blood velocities below 2.0 m/s may, for the present, be considered suitable for breeding. Other useful Grade 2 dogs might, for the present, be available for stud to a strictly limited number of bitches. These bitches should be murmur-free or have at the most only grade 1 murmurs. Dogs with Grade 3 or louder murmurs should never be considered for breeding purposes, even if they have blood velocities below 2.0 m/s.

3. Bitch owners are strongly advised to use only tested and proven normal dogs at stud.

4. Dog owners are advised to offer only tested and proven normal dogs for stud purposes and ensure, before accepting bitches for service, that their owners are complying with the recommended control procedures. At owners' risk, stud services could be provided for untested, non-show bitches both of whose parents are murmur-free or have only grade 1 murmurs.

5. Stock incidentally identified as having heart abnormalities other than aortic stenosis, eg, cardiomyopathy or pulmonic stenosis, should not be considered for breeding purposes.

B. In the case of young stock, ie, under 12 months of age:

Puppies aged 6 - 12 months can usefully be tested in the same manner as adults but the results must be interpreted with discretion. Because aortic stenosis develops progressively it cannot be assumed that those that are free of murmurs or have only grade 1 murmurs will be found to be so as adults; their prospects may nevertheless be considered relatively good. On the other hand, those found to have grade 2 or louder murmurs are unlikely to become suitable prospects for breeding purposes, and may be at risk of developing the clinical effects of aortic stenosis in later life. The testing of puppies is strongly recommended. Their retesting as adults is essential, however.

SPECIFIC BRITISH RECOMMENDATIONS FOR NEWFOUNDLAND BREEDERS REGARDING SAS (Dr Jo Dukes-McEwan)

In subaortic stenosis there may be NO murmur in a young pup. As the pup grows and the heart grows, the abnormality below the valve remains constant, so it becomes proportionately worse with ageing. This is the reason that dogs should be over 12 months old for the results of official heart testing to be recorded or published.  Although it is sensible to get pups checked, they must be re-examined at over 12 months old.  There is a possibility that SAS does become more severe up until 24 months of age, but then remains reasonably constant.
It has been shown (Jo Dukes-McEwan) that some Newfoundlands, being broad-chested, possibly over-weight, and tending to pant, have NO audible heart murmur. There is evidence of SAS on echo-Doppler. This shows that the sensitivity of heart testing by the stethoscope alone is insufficient to detect all cases of SAS (although it will certainly detect the more severe cases). This is the reason why dogs used at stud should be echo-Dopplered for SAS. Stud dogs are potentially responsible for many more progeny than bitches.
Dogs which had a heart murmur detected at 12 months old will mature and may put on a lot of weight and then the murmur becomes undetectable. Similarly, dogs with no heart murmur detected may lose a lot of weight, and then one becomes apparent.
Sub-aortic stenosis is the main congenital heart disease of concern in Newfoundland dogs.  Confirmation of diagnosis by echo-Doppler is based on a Doppler recording of a peak aortic velocity exceeding 1.7 metres per second in a relaxed dog. The blood flow through the aortic valve is normally much less than 1.7 m/s. Increased velocity is associated with increased turbulence of blood. These are both factors in creating a heart murmur. The abnormal flow is a consequence of a narrowed (stenotic) area affecting the aortic valve or caused by a fibrous ridge below the valve.


SPECIFIC BRITISH RECOMMENDATIONS FOR MITRAL VALVE DISEASE IN CAVALIER KING CHARLES SPANIELS

Mitral valvular endocardiosis (MVD) in Cavalier King Charles Spaniels (CKCS):  while it is extremely doubtful the disease will ever be irradicated from the Cavalier King Charles Spaniel completely, the hope of breeders is to move the age of onset back as late in life as possible. So many breeders will have their dogs checked annually for evidence of a heart murmur (via auscultation) and breed mature dogs which are unaffected. By breeding older Cavaliers who are clear of a murmur until as late as possible in life it is hoped that the age of onset will also move back as well.
The suggested protocol at present in many countries is to try to breed females who are older than 2 1/2 years of age and clear (with parents with clear heart certificates, issued at 5 (five) years or older), to males who are at least 2½ (two and a half) years old with a clear heart (with parents with clear heart certificates issued at 5 (five) years of age or older). To use an older stud dog with a clear certificate issued as late in life as possible is highly desirable.
Please remember, dogs do not have to have a clear heart to be used as stud. It is the dogs with early onset murmurs (under five years of age) that are strongly advised not to use for breeding. It is strongly advised that breeding stock under five years of age is limited to those with clear heart certificates. Breeders should aim at raising the age of onset of MVD by selecting breeding stock with a good heart record. Club guide-lines are based on current recommendations of Geneticists and Cardiologists, and may be updated and reissued as further research information becomes available.
Testing is merely a breeder's tool to try to establish a dog's health at any point in time. It does not mean that dog may not develop a heart murmur 3 months onwards or that he will not produce puppies with Mitral Valve Disease.